We propose a formal framework for interpretable machine learning. Combining elements from statistical learning, causal interventionism, and decision theory, we design an idealised explanation game in which players collaborate to find the best explanation for a given algorithmic prediction. Through an iterative procedure of questions and answers, the players establish a three-dimensional Pareto frontier that describes the optimal trade-offs between explanatory accuracy, simplicity, and relevance. Multiple rounds are played at different levels of abstraction, allowing the players to explore overlapping causal (...) patterns of variable granularity and scope. We characterise the conditions under which such a game is almost surely guaranteed to converge on a optimal explanation surface in polynomial time, and highlight obstacles that will tend to prevent the players from advancing beyond certain explanatory thresholds. The game serves a descriptive and a normative function, establishing a conceptual space in which to analyse and compare existing proposals, as well as design new and improved solutions. (shrink)

Machine learning algorithms may radically improve our ability to diagnose and treat disease. For moral, legal, and scientific reasons, it is essential that doctors and patients be able to understand and explain the predictions of these models. Scalable, customisable, and ethical solutions can be achieved by working together with relevant stakeholders, including patients, data scientists, and policy makers.

Many scholars have argued that the Protestant Reformation generally departed from virtue ethics, and this claim is often accepted by Protestant ethicists. This essay argues against such discontinuity by demonstrating John Calvin’s reception of ethical concepts from Augustine and Aristotle. Calvin drew on Augustine’s concept of eudaimonia and many aspects of Aristotle’s Nicomachean Ethics , including concepts of choice, habit, virtue as a mean, and the specific virtues of justice and prudence. Calvin also evaluated the problem of pagan virtue in (...) light of traditional Augustinian texts discussed in the medieval period. He interpreted the Decalogue as teaching virtue, including the cardinal virtues of justice and temperance. Calvin was not the harbinger of an entirely new ethical paradigm, but rather a participant in the mainstream of Christian thinkers who maintained a dual interest in Aristotelian and Augustinian eudaimonist virtue ethics. (shrink)

This is a brief introduction to the origin and development of Protestant ethical works in the tradition of Aristotle’s Nicomachean Ethics.

Richard Baxter, one of the most famous Puritans of the seventeenth century, is generally known as a writer of practical and devotional literature. But he also excelled in knowledge of medieval and early modern scholastic theology, and was conversant with a wide variety of seventeenth-century philosophies. Baxter was among the early English polemicists to write against the mechanical philosophy of René Descartes and Pierre Gassendi in the years immediately following the establishment of the Royal Society. At the same time, he (...) was friends with Robert Boyle and Matthew Hale, corresponded with Joseph Glanvill, and engaged in philosophical controversy with Henry More. In this book, David Sytsma presents a chronological and thematic account of Baxter's relation to the people and concepts involved in the rise of mechanical philosophy in late-seventeenth-century England. -/- Drawing on largely unexamined works, including Baxter's Methodus Theologiae Christianae (1681) and manuscript treatises and correspondence, Sytsma discusses Baxter's response to mechanical philosophers on the nature of substance, laws of motion, the soul, and ethics. Analysis of these topics is framed by a consideration of the growth of Christian Epicureanism in England, Baxter's overall approach to reason and philosophy, and his attempt to understand creation as an analogical reflection of God's power, wisdom, and goodness, understood as vestigia Trinitatis. Baxter's views on reason, analogical knowledge of God, and vestigia Trinitatis draw on medieval precedents and directly inform a largely hostile, though partially accommodating, response to mechanical philosophy. (shrink)

To the extent that dualism is even taken to be a serious option in contemporary discussions of personal identity and the philosophy of mind, it is almost exclusively either Cartesian dualism or property dualism that is considered. The more traditional dualism defended by Aristotelians and Thomists, what I call hylemorphic dualism, has only received scattered attention. In this essay I set out the main lines of the hylemorphic dualist position, with particular reference to personal identity. First I argue that overemphasis (...) of the problem of consciousness has had an unhealthy effect on recent debate, claiming instead that we should emphasize the concept of form. Then I bring in the concept of identity by means of the notion of substantial form. I continue by analyzing the relation between form and matter, defending the traditional theses of prime matter and of the unicity of substantial form. I then argue for the immateriality of the substantial form of the human person, viz. the soul, from an account of the human intellect. From this follows the soul's essential independence of matter. Finally, although the soul is the immaterial bearer of personal identity, that identity is still the identity of an essentially embodied being. I explain how these ideas are to be reconciled. Footnotesa I am grateful to Stephen Braude, John Cottingham, John Haldane, David Jehle, Joel Katzav, Eduardo Ortiz, and Fred Sommers for helpful comments and discussion of a draft of this essay. I would also like to thank Ellen Paul, whose suggestions have helped greatly to improve the essay's style and content. (shrink)

There is a tension between the reasonable desire not to be judgmental of other people’s behaviour or character, and the moral necessity of making negative judgments in some cases. I sketch a way in which we might accommodate both, via an evaluation of the good of reputation and the ethics of judgment of other people’s character and behaviour. I argue that a good reputation is a highly valuable good for its bearer, akin to a property right, and not to be (...) damaged without serious reason deriving from the demands of justice and the common welfare. Rash judgment wrongfully damages reputation and is sometimes a seriously immoral act. Rashness is not merely about lack of evidence, but involves lack of charity and is to be avoided even in some cases where the evidence of bad character or action is epistemically sufficient for judgment. I argue that the desirability of a good name for its holder, whether the reputation is deserved or not, means that in all but a relatively narrow range of cases it is always wrong to think badly of someone, even if they are bad. (shrink)

Corruptionism is the view that following physical death, the human being ceases to exist but their soul persists in the afterlife. Survivalism holds that both the human being and their soul persist in the afterlife, as distinct entities, with the soul constituting the human. Each position has its defenders, most of whom appeal both to metaphysical considerations and to the authority of St Thomas Aquinas. Corruptionists claim that survivalism violates a basic principle of any plausible mereology, while survivalists tend to (...) reject the principle, though without as much detail as one would like. In this paper I examine both the key exegetical issues and the mereological question, arguing that Aquinas cannot be shown to have supported the principle in question, and that the principle should be rejected on independent grounds. If correct, some key planks in support of survivalism are established, with others to await further examination. (shrink)

This essay examines the development of Reformed treatments of the affections in the period of early orthodoxy (ca. 1565-1640). I argue that discussion of the affections during this period grew within the broad framework of the Aristotelian psychology and certain polemical concerns initially established by early Reformed theologians. With the advent of Protestant universities and academies, Reformed ethicists and theologians treated the affections in greater detail, with a majority drawing on a generally Thomistic approach to the nature and division of (...) the affections, although not without a dissenting Scotistic minority. (shrink)

This critical edition is the first ever publication of Hale's Of the Law of Nature, which previously existed only in manuscript form. After discussing and defining the law in general, Hale examines the natural law in particular, its discovery and divine origin, and how it relates to both biblical and human laws. Hale's treatise, which was likely written as part of his personal meditations, and was circulated among English lawyers after his death, reveals not only the close relationship between law (...) and theology in his thought, but also the importance of natural law to early modern legal thought. (shrink)

In this paper, we propose a methodology to maximize the benefits of interdisciplinary cooperation in AI research groups. Firstly, we build the case for the importance of interdisciplinarity in research groups as the best means to tackle the social implications brought about by AI systems, against the backdrop of the EU Commission proposal for an Artificial Intelligence Act. As we are an interdisciplinary group, we address the multi-faceted implications of the mass-scale diffusion of AI-driven technologies. The result of our exercise (...) lead us to postulate the necessity of a behavioural theory that standardizes the interaction process of interdisciplinary groups. In light of this, we conduct a review of the existing approaches to interdisciplinary research on AI appliances, leading to the development of methodologies like ethics-by-design and value-sensitive design, evaluating their strengths and weaknesses. We then put forth an iterative process theory hinging on a narrative approach consisting of four phases: definition of the hypothesis space, building-up of a common lexicon, scenario-building, interdisciplinary self-assessment. Finally, we identify the most relevant fields of application for such a methodology and discuss possible case studies. (shrink)

This study aimed to understand the preserved elements of self-identity in persons with moderate to severe dementia attributable to Alzheimer’s disease. A semi-structured interview was developed to explore the narrative self among residents with dementia in a residential care facility and residents without dementia in an independent living setting. The interviews were transcribed verbatim from audio recordings and analyzed for common themes, while being sensitive to possible differences between the groups. The participants with dementia showed evidence of self-reference even though (...) losses in explicit memory were evident. The most noticeable difference between the two groups was time frame reference. Nonetheless, all participants showed understanding of their role in relationships and exhibited concrete preferences. Our findings suggest that memory loss and other cognitive deficits associated with moderate to severe dementia do not necessarily lead to a loss of “self.”. (shrink)

Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...) by several alleles (shared epitopes) are better descriptors of the actual causative genetic variants. Here we describe a novel approach to genetic association analysis in which genes/proteins are broken down into smaller sequence features and then variant types defined for each feature, allowing for independent analysis of disease association with each sequence feature variant type. We have used this approach to analyze a cohort of systemic sclerosis patients and show that a sequence feature composed of specific amino acid residues in peptide binding pockets 4 and 7 of HLA-DRB1 explains much of the molecular determinant of risk for systemic sclerosis. (shrink)

Context — Children and adults with psychopathic traits and conduct or oppositional defiant disorder demonstrate poor decision making and are impaired in reversal learning. However, the neural basis of this impairment has not previously been investigated. Furthermore, despite high comorbidity of psychopathic traits and attention deficit/hyperactivity disorder, to our knowledge, no research has attempted to distinguish neural correlates of childhood psychopathic traits and attention-deficit/hyperactivity disorder. Objective—To determine the neural regions that underlie the reversal learning impairments in children with psychopathic traits (...) plus conduct or oppositional defiant disorder. Design — Case-control study. Setting — Government clinical research institute. Participants — Forty-two adolescents aged 10 to 17 years: 14 with psychopathic traits and oppositional defiant disorder or conduct disorder, 14 with attention-deficit/hyperactivity disorder only, and 14 healthy controls. Main Outcome Measure — Blood oxygenation level–dependent signal as measured via functional magnetic resonance imaging during a probabilistic reversal task. Results — Children with psychopathic traits showed abnormal responses within the ventromedial prefrontal cortex (Brodmann area 10) during punished reversal errors compared with children wit hattention deficit/hyperactivity disorder and healthy children (P < .05 corrected for multiple comparisons). Conclusions — To our knowledge, this study provides the first evidence of abnormal ventromedial prefrontal cortex responsiveness in children with psychopathic traits and demonstrates this dysfunction was not attributable to comorbid attention-deficit/hyperactivity disorder. These findings suggest that reversal learning impairments in patients with developmental psychopathic traits relate to abnormal processing of reinforcement information. (shrink)

Beyond Dordt and ‘De Auxiliis’ explores post-Reformation inter-confessional theological exchange on soteriological topics including predestination, grace, and free choice. These doctrines remained controversial within confessional traditions after the Reformation, as Dominicans and Jesuits and later Calvinists and Arminians argued about these critical issues in the Augustinian theological heritage. Some of those involved in condemning Arminianism at the Synod of Dordt (1618-1619) were inspired by Dominican followers of Thomas Aquinas in Spain who had recently opposed the vigorous defense of free choice (...) by Jesuit Molinists in the Congregatio de auxiliis (1598-1607). This volume, appearing on the 400th anniversary of the closing of the Synod of Dordt, brings together a group of scholars working in fields that only rarely speak to one another to address these theological debates that cross geographical and confessional boundaries. (shrink)

Is the societal-level of analysis sufficient today to understand the values of those in the global workforce? Or are individual-level analyses more appropriate for assessing the influence of values on ethical behaviors across country workforces? Using multi-level analyses for a 48-society sample, we test the utility of both the societal-level and individual-level dimensions of collectivism and individualism values for predicting ethical behaviors of business professionals. Our values-based behavioral analysis indicates that values at the individual-level make a more significant contribution to (...) explaining variance in ethical behaviors than do values at the societal-level. Implicitly, our findings question the soundness of using societal-level values measures. Implications for international business research are discussed. (shrink)

The computational genomics community has come increasingly to rely on the methodology of creating annotations of scientific literature using terms from controlled structured vocabularies such as the Gene Ontology (GO). We here address the question of what such annotations signify and of how they are created by working biologists. Our goal is to promote a better understanding of how the results of experiments are captured in annotations in the hope that this will lead to better representations of biological reality through (...) both the annotation process and ontology development, and in more informed use of the GO resources by experimental scientists. (shrink)

Traditionally, the investigation of truth has been anchored in a priori reasoning. Cognitive science deviates from this tradition by adding empirical data on how people understand and use concepts. Building on psychophysics and machine learning methods, we introduce conceptual scaling, an approach to map people's understanding of abstract concepts. This approach, allows computing participant-specific conceptual maps from obtained ordinal comparison data, thereby quantifying perceived similarities among abstract concepts. Using this approach, we investigated individual's alignment with philosophical theories on truth and (...) the predictive capacity of conceptual maps. The obtained results indicated that, while people's understanding of truth is multifaceted and encapsulates notions of coherence and authenticity, alignment is best for the correspondence theory of truth. Furthermore, conceptual maps allowed predicting individual outcomes with an accuracy of roughly 70%. This research demonstrates that conceptual scaling offers accurate descriptions of individual's understanding of abstract concepts, behavioral predictions, and quantification of alignment with theoretical perspectives. (shrink)

Derek Parfit, in On What Matters, argues that all subjective accounts of normative reasons for action are false. This chapter focuses on his “Agony Argument.” The first premise of the Agony Argument is that we necessarily have current reasons to avoid our own future agony. Its second premise is that subjective accounts cannot vindicate this fact. So, the argument concludes, subjective accounts must be rejected. This chapter accepts the first premise of this argument and that it is valid. The main (...) thesis of this chapter is that subjectivists can account for our reasons to get pleasure and avoid agony. The chapter concludes that the Agony Argument does not justify the rejection of subjective accounts. The chapter also examines Parfit's understanding of the distinction between objective and subjective theories. The chapter claims Parfit offers a surprisingly narrow understanding of subjectivism such that even if his critique were successful, this would be bad news for fewer theories than we might have thought. Finally, the chapter replies to some possible worries about the arguments of this chapter. (shrink)

Behavioral genetic (BG) research has yielded many important discoveries about the origins of human behavior, but offers little insight into how we might improve outcomes. We posit that this gap in our knowledge base stems in part from the epidemiologic nature of BG research questions. Namely, BG studies focus on understanding etiology as it currently exists, rather than etiology in environments that could exist but do not as of yet (e.g., etiology following an intervention). Put another way, they focus exclusively (...) on the etiology of “what is” rather than “what could be”. The current paper discusses various aspects of this field-wide methodological reality, and offers a way to overcome it by demonstrating how behavioral geneticists can incorporate an experimental approach into their work. We outline an ongoing study that embeds a randomized intervention within a twin design, connecting “what is” and “what could be” for the first time. We then lay out a more general framework for a new field—experimental BGs—which has the potential to advance both scientific inquiry and related philosophical discussions. (shrink)

Recent research on the metaethical beliefs of ordinary people appears to show that they are metaethical pluralists that adopt different metaethical standards for different moral judgments. Yet the methods used to evaluate folk metaethical belief rely on the assumption that participants interpret what they are asked in metaethical terms. We argue that most participants do not interpret questions designed to elicit metaethical beliefs in metaethical terms, or at least not in the way researchers intend. As a result, existing methods are (...) not reliable measures of metaethical belief. We end by discussing the implications of our account for the philosophical and practical implications of research on the psychology of metaethics. (shrink)

In a recent paper, Firt, Hemmo and Shenker argue that Hempel’s dilemma, typically thought to primarily undermine physicalism, is generalizable and impacts mind-body dualism and many other theories equally. I challenge this view and argue that Hempel’s dilemma admits of at least two distinct construals: a general-skeptical construal, underpinned by historically driven arguments such as the pessimistic induction, and a non-skeptical construal, driven by the specific puzzles and volatility of current physics. While the general-skeptical construal applies to all changeable deep-structure (...) theories, the non-skeptical construal primarily targets volatile theories which harbor exclusionary ambitions. As a result, dualism largely evades both construals due to the stability of theories of the mental and their lack of exclusionary ambitions. Conversely, physicalism is uniquely susceptible to both construals due to its strong commitment to deep-structure realism, inherent exclusionary ambitions, and the volatility of certain branches of fundamental physics. The paper ultimately concludes that Hempel’s dilemma is not universally problematic, but presents a unique challenge to physicalism while being relatively congenial to dualism. (shrink)

The principal thesis in this review-essay is that the key linguistic terms in Fichte’s Wissenschaftslehre especially have two main meanings that appear at first sight to be almost in contradiction or opposed to each other. The reader of Fichte therefore has to work hard to overcome any apparent conflicts in the “double sense” of his philosophical terminology. Accordingly, I argue that Fichte’s linguistic method and use of language should be seen as part of his chief philosophical method of synthesis, where (...) we have to carry out a similar procedure and attempt to reconcile opposites using the power of the imagination. This thesis is put forward by means of a number of practical examples and in the context of some critical reflections on the recently published Cambridge Companion to Fichte, eds. David James and Günter Zöller. Review essay published in Volume 15 (December, 2017) of the journal Revista de Estud(i)os sobre Fichte (ed. Emiliano Acosta). (shrink)

Shepherd’s argument against Hume’s thesis that an object can begin its existence uncaused has received short shrift in the secondary literature. I argue that the key to understanding that argument’s success is understanding its dialectical context. Shepherd sees the dialectical situation as follows. Hume presents an argument against Locke and Clarke the conclusion of which is that an object can come into existence uncaused. An essential premise of that argument is Hume’s theory of mental representation. Hume’s theory of mental representation, (...) however, is itself implausible and unsupported. Therefore, one need not accept this premise or this conclusion. Thus, Shepherd proceeds to her discussion of the relation of cause and effect free to help herself to the thesis that every beginning of existence must have a cause. Additionally, she elsewhere pays down the debt she incurs in that argument by presenting her own alternative theory of mental representation, which is both plausible in its own right, and can account for the error that she takes Hume to make. (shrink)

According to Richard Gelwick, one of the fundamental implications of Polanyi’s epistemology is that all intellectual disciplines are inherently heuristic. This article draws out the implications of a heuristic vision of theology latent in Polanyi’s thought by placing contemporary theologian David Brown’s dynamic understanding of tradition, imagination, and revelation in the context of a Polanyian-inspired vision of reality. Consequently, such a theology will follow the example of science, reimagining its task as one of discovery rather than mere reflection on (...) a timeless body of divine revelation. The ongoing development of a theological tradition thus involves the attempt to bring one’s understanding of the question of God to bear on the whole of the human experience. The pursuit of theology as a heuristic endeavor is a bold attempt to construct an integrated vision of nothing less than the entirety of all that is, without absolutizing one’s vision, and without giving up on the question of truth. (shrink)

Plato's Phaedo is a literary gem that develops many of his most famous ideas. David Ebrey's careful reinterpretation argues that the many debates about the dialogue cannot be resolved so long as we consider its passages in relative isolation from one another, separated from their intellectual background. His book shows how Plato responds to his literary, religious, scientific, and philosophical context, and argues that we can only understand the dialogue's central ideas and arguments in light of its overall structure. (...) This approach yields new interpretations of the dialogue's key ideas, including the nature and existence of 'Platonic' forms, the existence of the soul after death, the method of hypothesis, and the contemplative ethical ideal. Moreover, this comprehensive approach shows how the characters play an integral role in the Phaedo's development and how its literary structure complements Socrates' views while making its own distinctive contribution to the dialogue's drama and ideas. (shrink)

This essay attempts to provide and defend what may be the first actual argument in support of P. F. Strawson's merely stated vision of a response-dependent theory of moral responsibility. It does so by way of an extended analogy with the funny. In part 1, it makes the easier and less controversial case for response-dependence about the funny. In part 2, it shows the tight analogy between anger and amusement in developing the harder and more controversial case for response-dependence about (...) a kind of blameworthiness. It then defends the view from three serious skeptical challenges. (shrink)

This essay connects Kafka's German and his Jewish linguistic sources, and explores the trans-national perspective on literary tradition they helped him create. I begin with a critique of Deleuze and Guattari's view of Kafka as a minority writer, showing how their cold war nationalism scants the positive contributions that Yiddish and Hebrew made to his work. I continue with an examination of the "twilight of containment," when this postcontemporary Kafka began to break through his cold war canonization after 1989. Other (...) sections include: "German-Jewish Traditions: The Echoes of Yiddish," on Kafka's cultural politics; "Hebrew: Zionism in a Transnational Key"; and "Goethe's Jewish Voices," on Yiddish as a model for Kafka's new conception of national writing. I conclude by considering the Jewish and other sources of Kafka's "linguistic turn," and the general, transnational focus on tradition that Jewish languages brought to his classic texts. (shrink)

Lipsey and Lancaster's "general theory of second best" is widely thought to have significant implications for applied theorizing about the institutions and policies that most effectively implement abstract normative principles. It is also widely thought to have little significance for theorizing about which abstract normative principles we ought to implement. Contrary to this conventional wisdom, I show how the second-best theorem can be extended to myriad domains beyond applied normative theorizing, and in particular to more abstract theorizing about the normative (...) principles we should aim to implement. I start by separating the mathematical model used to prove the second-best theorem from its familiar economic interpretation. I then develop an alternative normative-theoretic interpretation of the model, which yields a novel second best theorem for idealistic normative theory. My method for developing this interpretation provides a template for developing additional interpretations that can extend the reach of the second-best theorem beyond normative theoretical domains. I also show how, within any domain, the implications of the second-best theorem are more specific than is typically thought. I conclude with some brief remarks on the value of mathematical models for conceptual exploration. (shrink)

The sense of balance remains a Cinderella among our senses. Although the vestibular apparatus and the apprehension of motion, equilibrium and orientation which it serves has now been studied extensively and descriptions abound in textbooks on perceptual psychology, its key role in our agency remains neglected in philosophical accounts of perception. Popularly received wisdom on the senses also largely ignores balance and it has recently even been called 'the lost sense'. -/- Recognition for the discovery of this sense should probably (...) be accorded to Thomas Reid and his contemporary William Charles Wells. Both made crucial observations before the close of the eighteenth century. Since there is now a tendency to emphasize the role of the agent, brain plasticity, and the development of motor skills in all perceptual tasks, some of Reid's comments in particular strike us as remarkably modern. Reid also differs from many authorities in crediting the sense with specific sensations, as would be expected given the role of sensations in his epistemological scheme. -/- In this paper some of the fascinating facts about the sense of balance are reviewed so that Reid's remarks can be evaluated in a modern context. Similarities and differences in the approaches of Wells and Reid are considered and the value that Reid's insights have even now in understanding perceptual processes is explored. It is suggested that Reid should indeed be counted among the hitherto unacknowledged discoverers of this fundamental sense. (shrink)

In their monograph Narrow Content, Yli-Vakkuri and Hawthorne argue that all versions of internalism about mental content are either false or "pointless" (roughly, of no interest). We overview Yli-Vakkuri and Hawthorne's main line of argument and suggest that, while largely correct, it does not touch the core internalist claim that mental states have internally determined contents. Instead of engaging with this claim, Yli-Vakkuri and Hawthorne attack a variety of stronger or weaker claims. The stronger claims fall prey to the Mirror (...) Man argument and other considerations. The weaker claims fall prey to the charge of pointlessness. But the core internalist view is left untouched. (shrink)

Although most agree that St. Anselm’s ontological argument is problematic, there is no consensus as to what, exactly, is the flaw in the argument. In this essay, I propose what I take to be a novel criticism of the argument. Specifically, I claim that Anselm is guilty of an equivocation in his use of the word “God,” using it sometimes to refer to a being and sometimes to refer to a concept. Any attempt to remove this equivocation, I show, is (...) doomed to failure; it is impossible to render the argument (or some version thereof) sound. (shrink)

Editor's Preface to Fichte-Studien 49 (2021), "The Enigma of Fichte’s First Principles", (Leiden/Boston: Brill, 2021): : IX-XIX. Also available on open-access. See the publisher's website.

Edited proceedings of an interdisciplinary symposium on consciousness held at the University of Cambridge in January 1978. Includes a foreword by Freeman Dyson. Chapter authors: G. Vesey, R.L. Gregory, H.C. Longuet-Higgins, N.K. Humphrey, H.B. Barlow, D.M. MacKay, B.D. Josephson, M. Roth, V.S. Ramachandran, S. Padfield, and (editorial summary only) E. Noakes. A scanned pdf is available from this web site (philpapers.org), while alternative versions more suitable for copying text are available from https://www.repository.cam.ac.uk/handle/1810/245189. -/- Page numbering convention for the pdf version (...) viewed in a pdf viewer is as follows: 'go to page n' accesses the pair of scanned pages 2n and 2n+1. Applicable licence: CC Attribution-NonCommercial-ShareAlike 2.0. (shrink)

Arthur Pap worked in analytic philosophy while maintaining a strong Kantian or neo-Kantian element throughout his career, stemming from his studying with Ernst Cassirer. I present these elements in the different periods of Pap’s works, showing him to be a consistent critic of logical empiricism, which Pap shows to be incapable of superseding the Kantian framework. Nevertheless, Pap’s work is definitely analytic philosophy, both in terms of the content and the style. According to Pap, the central topics of analytic philosophy (...) concern meaning, modality, and analysis. Pap was also influenced by pragmatism, especially in his dissertation, although he does not fully embrace it in either its classical or its Quinean form. (shrink)

Debiasing procedures are experimental methods aimed at correcting errors arising from the cognitive biases of the experimenter. We discuss two of these methods, the predesignation rule and randomization, showing to what extent they are open to the experimenter’s regress: there is no metarule to prove that, after implementing the procedure, the experimental data are actually free from biases. We claim that, from a contractarian perspective, these procedures are nonetheless defensible since they provide a warrant of the impartiality of the experiment: (...) we only need proof that the result has not been intentionally manipulated for prima facie acceptance. (shrink)

In this thesis I offer an interpretation of Arthur Schopenhauer’s pessimism. I argue against interpreting Schopenhauer’s pessimism as if it were merely a matter of temperament, and I resist the urge to find a single standard argument for pessimism in Schopenhauer’s work. Instead, I treat Schopenhauer’s pessimism as inherently variegated, composed of several distinct but interrelated pessimistic positions, each of which is supported by its own argument. I begin by examining Schopenhauer’s famous argument that willing necessitates suffering, which I defend (...) against the misrepresentative interpretation advocated by Ivan Soll. I also offer a metaphysical reading of Schopenhauer’s claim that no amount happiness can compensate for the mere fact of suffering, based upon his negative conception of happiness. I proceed by analysing Schopenhauer’s criticisms of two prominent optimists, Leibniz and Rousseau. I attempt to salvage something of Schopenhauer’s counterargument against Leibniz that this is the worse of all possible worlds, and I also examine Schopenhauer’s claim that the optimistic metaphysics of a priori rationalistic philosophy cannot cope with the evidence of meaningless suffering. In the case of Rousseau, I interpret Schopenhauer’s brief objection to Rousseau’s assumption of original goodness, by means of an examination of Schopenhauer’s conception of the contrary doctrine, original sin. Next I consider the metaphysics of Schopenhauer’s account of eternal justice. After defending it against a number of objections, I argue that the nature of his version of eternal justice, which he admits constitutes a justification for suffering, does not conflict with the fact that he so strongly condemns Leibniz’s and Rousseau’s optimistic justifications for suffering. Finally I assess whether and to what extent Schopenhauer’s ethics of salvation are either pessimistic or optimistic. I conclude that the mere fact that salvation is possible is not necessarily a cause for optimism, but that Schopenhauer’s doctrine of salvation is made partly optimistic by the higher form of cognition that he describes as part of it. I also argue that Schopenhauer’s views on the essentially mystical nature of the state of salvation ultimately commit him to being neither positively optimistic nor positively pessimistic about salvation. I conclude overall with some brief remarks about the meaning of Schopenhauer’s pessimism, and how in spite of its diverse nature, it is able to lay down a singular challenge to all future philosophers concerned with the question of suffering. (shrink)

El amor cristiano es una exigencia que pretende la superación del egoísmo y el fomento del desarrollo positivo de las relaciones humanas al ayudar a los demás a ser independientes. No obstante, Søren Kierkegaard ha señalado en su obra que existen obstáculos mundanos y problemáticos que impiden que este tipo de amor se materialice efectivamente. Así pues, el objetivo de este texto es exponer el concepto de amor cristiano como exigencia ética radical y su capacidad como correctivo para las relaciones (...) humanas problemáticas en la sociedad a partir de Las obras del amor. Para esto, en primer lugar, expongo la vida oculta del amor, seguido de la descripción del amor de predilección, que es la forma particularizada del amor. Finalmente, me dispondré a dilucidar la exigencia radical del amor, en virtud de hallar la esencia del amor y cómo podría ser un correctivo para la práctica en las relaciones interpersonales de la sociedad. (shrink)

Research in pharmacogenomics and precision medicine has recently introduced the concept of Polygenic Scores (PGSs), namely, indexes that aggregate the effects that many genetic variants are predicted to have on individual disease risk. The popularity of PGSs is increasing rapidly, but surprisingly little attention has been paid to the idealisations they make about phenotypic development. Indeed, PGSs rely on quantitative genetics models and methods, which involve considerable theoretical assumptions that have been questioned on various grounds. This comes with epistemological and (...) ethical concerns about the use of PGSs in clinical decision-making. In this paper, I investigate to what extent idealisations in genetics models can impact the data gathering and clinical interpretation of genomics findings, particularly the calculation and predictive accuracy of PGSs. Although idealisations are considered ineliminable components of scientific models, they may be legitimate or not depending on the epistemic aims of a model. I thus analyse how various idealisations have been introduced in classical models and progressively readapted throughout the history of genetic theorising. Notably, this process involved important changes in the epistemic purpose of such idealisations, which raises the question of whether they are legitimate in the context of contemporary genomics. (shrink)

This chapter examines the ethical matters that arise from Schopenhauer’s discussions of sexual love and sexual practices. It presents Schopenhauer's remarks on “pederasty”, among other “unnatural lusts”, and attempts to disentangle Schopenhauer’s judgements on these practices from the principles that guide them. It considers these practices in the light of Schopenhauer's ethics of asceticism and his ethics of compassion and concludes that Schopenhauer’s objections to them are not always moral in nature, strictly speaking, and where they are moral, they are (...) not always based on the “unnaturalness” of the practices, but rather the harm that he supposes they may cause. (shrink)

Wittgenstein’s writings and lectures during the first half of the 1930s play a crucial role in any interpretation of the relationship between the Tractatus and the Philosophical Investigations . G. E. Moore’s notes of Wittgenstein’s Cambridge lectures, 1930-1933, offer us a remarkably careful and conscientious record of what Wittgenstein said at the time, and are much more detailed and reliable than previously published notes from those lectures. The co-authors are currently editing these notes of Wittgenstein’s lectures for a book to (...) be published by Cambridge University Press. We describe the materials that make up Moore’s notes, explain their unique value, review the principal editorial challenges that these materials present, and provide a brief outline of our editorial project. (shrink)

John Fischer has attacked the Ockhamistic solution to the freedom–foreknowledge dilemma by arguing that: (1) God's prior beliefs about the future, though being soft facts about the past, are soft facts of a special sort, what he calls ‘hard-type soft facts’, i.e. soft facts, the constitutive properties of which are ‘hard’, or ‘temporally non-relational properties’; (2) in this respect, such facts are like regular past facts which are subject to the fixity of the past. In this paper, I take issue (...) with this argument by Fischer, claiming that it does not succeed for two reasons: (i) Fischer's account of the notion of a hard property is unsatisfactory; (ii) his notion of a hard-type soft fact is incoherent. Despite this criticism, I agree with Fischer that there is a fundamental difference between God's beliefs about the future and regular soft facts with regard to their fixity-status, but I argue that the reason for this difference is that God's forebeliefs are plain hard facts about the past. (shrink)

This article analyses how the French Academy of Sciences assessed Jaime Ferrán’s cholera vaccine submitted for the Prix Bréant in the 1880s. Ferrán, a Spanish independent physician, discovered the treatment in 1884 and tried it on thousands of patients during the cholera outbreak in Valencia the following year. His evaluation sparked a controversy in Spain and abroad on the vaccine’s efficacy. The Bréant jury did not see any evidence for it in Ferrán’s submission, a decision usually interpreted in terms of (...) French scientific nationalism (or simple chauvinism): an outsider from the scientific periphery could not be awarded the Bréant. Drawing on the archival records of the award, we suggest that Ferrán failed instead to provide data that the Academy could consider unbiased, according to the contemporary standards for data presentation. We will illustrate these standards at work in the assessment of another submission from Spain, by Philipp Hauser, who received the Bréant for the thoroughness of his statistical endeavour. (shrink)

Explores five fault lines in the fledgling field of responsibility theory, serious methodological disputes traceable to P.F. Strawson's "Freedom and Resentment.".

In introducing the reactive attitudes “of people directly involved in transactions with each other,” P. F. Strawson lists “gratitude, resentment, forgiveness, love, and hurt feelings.” To show how our interpersonal emotional practices of responsibility could not be undermined by determinism’s truth, Strawson focused exclusively on resentment, specifically on its nature and actual excusing and exempting conditions. So have many other philosophers theorizing about responsibility in Strawson’s wake. This method and focus has generated a host of quality of will theories of (...) responsibility. What I show in this paper is that if Strawson—and his followers—had focused on hurt feelings instead of resentment, not only would quality of will theories of responsibility be disfavored, but none of our other theories of responsibility could adequately account for them. I conclude by exploring what a conundrum this poses for our methods and starting points in theorizing about responsibility. (shrink)

In this paper, I analyze the ethical implications of genetic enhancement within the specific framework of the “child’s right to an open future” argument (CROF). Whilst there is a broad ethical consensus that genetic modifications for eradicating diseases or disabilities are in line with – or do not violate – CROF, there is huge disagreement about how to ethically understand genetic enhancement. Here, I analyze this disagreement and I provide a revised formulation of the argument in the specific field of (...) genetic enhancement. First, I argue that CROF is not in contrast with every kind of enhancement. I subsequently discuss whether CROF requires some moral obligations to enhance progeny. My argument is that parents do not have the moral obligation to open as many options as possible for their children. Rather, they should provide them with a reasonable range of opportunities. Finally, I contend that the moral obligations required by CROF are directly dependent on what Allen Buchanan calls the ‘dominant cooperative framework’ in a given society. I conclude by claiming that, at present, parents are not morally obliged to genetically enhance their children since a non-enhanced person already might have access to a reasonable range of opportunities. However, the moral obligation to enhance progeny might arise if a structural modification of the dominant cooperative framework occurs. (shrink)

Epistemologists have recently proposed a number of norms governing rational inquiry. My aim in this paper is to unify and explain recently proposed norms of inquiry by developing a general account of the conditions under which inquiries are rational, analogous to theories such as evidentialism and reliabilism for rational belief. I begin with a reason-responsiveness conception of rationality as responding correctly to possessed normative reasons. I extend this account with a series of claims about the normative reasons for inquiry that (...) we possess. I apply the account to shed light on two classes of norms that have featured prominently in recent discussions: norms of clutter avoidance forbidding agents from engaging in trivial inquiries, and norms of logical non-omniscience governing properties such as the deductive closure and consistency of an agent's belief state. I conclude with a discussion of the sense in which norms of inquiry should be regarded as epistemic norms. (shrink)